Worley G, Claerhout S J, Combs S P
Department of Pediatrics, Duke University Medical Center, Durham, North Carolina 27710, USA.
Clin Pediatr (Phila). 1998 Jun;37(6):347-52. doi: 10.1177/000992289803700603.
Hypophosphatemia in malnourished children during nutritional recovery (refeeding hypophosphatemia) is recognized as a cause of morbidity and mortality in adolescents with anorexia nervosa but has been only rarely reported to occur in younger children with other diagnoses. Over a 6-year period, we encountered three cases of refeeding hypophosphatemia in malnourished children admitted to a pediatric rehabilitation hospital. Two children had neurologic dysphagia and one had been starved by an abusive parent. The one patient who was symptomatic had obtundation, hemolytic anemia, rhabdomyolysis, and hepatocellular injury that began during refeeding and resolved with treatment. The signs and symptoms, pathophysiology, and treatment of refeeding hypophosphatemia are reviewed.
营养不良儿童在营养恢复过程中出现的低磷血症（再喂养低磷血症）被认为是神经性厌食青少年发病和死亡的一个原因，但在患有其他诊断的年幼儿童中仅有罕见报道。在6年期间，我们在一家儿科康复医院收治的营养不良儿童中遇到了3例再喂养低磷血症病例。两名儿童患有神经性吞咽困难，一名儿童曾被虐待父母饿肚子。有症状的那名患者在再喂养期间出现意识模糊、溶血性贫血、横纹肌溶解和肝细胞损伤，并经治疗后痊愈。本文对再喂养低磷血症的体征和症状、病理生理学及治疗进行了综述。
