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胃息肉的组织学类型与监测:一项七年的临床病理研究

Histologic types and surveillance of gastric polyps: a seven year clinico-pathological study.

作者信息

Papa A, Cammarota G, Tursi A, Montalto M, Cuoco L, Certo M, Fedeli G, Gasbarrini G

机构信息

Department of Internal Medicine, Catholic University of Rome, Italy.

出版信息

Hepatogastroenterology. 1998 Mar-Apr;45(20):579-82.

PMID:9638455
Abstract

BACKGROUND/AIMS: This is a seven-year prospective study based on all gastroscopic examinations of our patient population in order to study gastric polyps.

METHODOLOGY

One hundred and twenty-one polyps, removed from 96 patients were analysed. All polyps, after endoscopic polypectomy, were classified according to their histotype. The follow-up was carried out in 49 patients for a mean time of 40 months.

RESULTS

Polypoid lesions were more frequent in females (57.3%) and they were preferentially located in antrum (60.3%). Hyperplastic and inflammatory polyps were 55.4% and 28.9%, respectively, while adenomatous lesions were 9.9%. Four fundic gland polyps, 1 carcinoid, 1 type I early gastric cancer and 1 pancreatic heterotopia were also found. During the follow-up no malignant lesion was encountered. On the other hand 25 benign polyps were found in 19 patients.

CONCLUSIONS

Our experience confirms that there is a close relationship between the size of the polyps and the neoplastic change. In fact, in our series all polyps were smaller than 2 cm and only one malignancy was found (an early gastric cancer). None of adenomatous polyps was associated with gastric adenocarcinoma. Our data also indicates that when a polypectomy is carried out for small polyps (smaller than 2 cm.) a strict follow-up is necessary for the neoplastic polyps only.

摘要

背景/目的:这是一项为期七年的前瞻性研究,基于对我们患者群体的所有胃镜检查来研究胃息肉。

方法

分析了从96例患者身上切除的121个息肉。所有息肉在内镜下切除后,根据其组织类型进行分类。对49例患者进行了随访,平均随访时间为40个月。

结果

息肉样病变在女性中更为常见(57.3%),且多位于胃窦部(60.3%)。增生性息肉和炎性息肉分别占55.4%和28.9%,而腺瘤性病变占9.9%。还发现了4个胃底腺息肉、1个类癌、1例I型早期胃癌和1例胰腺异位。随访期间未发现恶性病变。另一方面,在19例患者中发现了25个良性息肉。

结论

我们的经验证实息肉大小与肿瘤性改变之间存在密切关系。事实上,在我们的系列研究中,所有息肉均小于2 cm,仅发现1例恶性肿瘤(1例早期胃癌)。腺瘤性息肉均未与胃腺癌相关。我们的数据还表明,当对小息肉(小于2 cm)进行息肉切除时,仅对肿瘤性息肉进行严格随访是必要的。

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