Ruiz-Contreras J, Bastero R, Serrano C, Benavent M I, Martinez A
Department of Pediatrics, Hospital Universitario 12 de Octubre, Madrid, Spain.
Eur J Radiol. 1998 May;27(2):149-52. doi: 10.1016/s0720-048x(97)00049-1.
A 14 year-old boy with X-linked chronic granulomatous disease (CGD) developed a long smooth narrowing at the mid oesophagus with severe dysphagia. Endoscopy revealed a normal mucosa and biopsy showed non-specific acute inflammatory changes. Bacterial cultures of the biopsy specimens were sterile. Combined treatment with antibiotics and steroids resulted in a transitory remission, but symptoms recurred after 2.5 months. One second course of steroids and antibiotics lead to a long-term remission. Oesophagogram was more useful than endoscopy to evaluate the severity of the stricture.
一名患有X连锁慢性肉芽肿病（CGD）的14岁男孩在食管中部出现了一段长而光滑的狭窄，并伴有严重吞咽困难。内镜检查显示黏膜正常，活检显示非特异性急性炎症改变。活检标本的细菌培养无菌。抗生素和类固醇联合治疗导致病情暂时缓解，但2.5个月后症状复发。第二个疗程的类固醇和抗生素治疗导致了长期缓解。食管造影在评估狭窄严重程度方面比内镜检查更有用。
