蛛网膜下腔灌注对实验性脊髓损伤中血栓素A和前列环素的影响。
Effect of intra-arachnoid space perfusion on thromboxane A and prostacycline in experimental spinal cord injury.
作者信息
Tu Y, Du J, Xia Z, Wang L
机构信息
Department of Orthopedics, Xiehe Hospital, Tongji Medical University, Wuhan.
出版信息
J Tongji Med Univ. 1997;17(1):40-3, 53. doi: 10.1007/BF02888001.
PMID:9639784
Abstract
In order to understand the relation between TXA2-PGI2 and secondary trauma and the effect of intra-arachnoid perfusion of dexamethasone and verapamil on alteration of TXA2-PGI2 following spinal cord injury, TXB2 and 6-keto-PGF alpha concentration and pathological changes in injured site 1, 2, 4, and 6 h after injury were studied using a rabbit spinal cord injury model by Allen's weight drop method.
摘要
为了解血栓素A2-前列环素（TXA2-PGI2）与继发性创伤的关系，以及地塞米松和维拉帕米蛛网膜下腔灌注对脊髓损伤后TXA2-PGI2变化的影响，采用Allen法兔脊髓损伤模型，研究损伤后1、2、4和6小时损伤部位的血栓素B2（TXB2）和6-酮-前列腺素Fα（6-keto-PGFα）浓度及病理变化。
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