Idris M N, Sokrab T E
Department of Medicine, Faculty of Medicine, University of Khartoum, Sudan.
East Afr Med J. 1998 Feb;75(2):127-8.
Clinical, laboratory and radiological features of two cases of hypoparathyroidism presenting with pure neurological disease are described. The first patient has choreoathetosis and the second has mutism, locked jaw bilateral papilloedema and generalised tonic clonic epilepsy. Computerised tomography of the brain showed extensive calcification in the gray and white matter in both cases. Such combination of neurological manifestation of the disease and extensive cerebral calcification is rarely encountered and reported. It is concluded that brain calcification, which is generally believed to be asymptomatic, can cause frank neurological disease when it is extensive.
描述了两例以单纯神经系统疾病为表现的甲状旁腺功能减退症患者的临床、实验室及影像学特征。首例患者有舞蹈手足徐动症，第二例患者有缄默症、牙关紧闭、双侧视乳头水肿及全身强直阵挛性癫痫。两例患者的脑部计算机断层扫描均显示灰质和白质广泛钙化。这种疾病的神经系统表现与广泛脑钙化的组合很少见且鲜有报道。得出的结论是，通常认为无症状的脑钙化在广泛时可导致明显的神经系统疾病。
