Pedersen N L, Berg S, Johansson B, Johansson K, Viitanen M, Winblad B, Gatz M
Institutet för miljömedicin, Karolinska institutet.
Lakartidningen. 1998 May 27;95(22):2585-8.
Genetic and environmental risk factors are central concerns in dementia research. Through twin studies one can study the relative importance of genetic and environmental risk factors. One such study, based on the Swedish Twin Registry, shows that genetic effects are of considerable importance for developing Alzheimer's disease, even late in life, but that environmental factors are also important. For vascular dementia, the results indicate that non-genetic factors are of primary importance.
遗传和环境风险因素是痴呆症研究的核心关注点。通过双胞胎研究,可以探究遗传和环境风险因素的相对重要性。一项基于瑞典双胞胎登记处的此类研究表明,遗传效应对于患阿尔茨海默病具有相当重要的作用,即使在晚年也是如此,但环境因素同样重要。对于血管性痴呆,研究结果表明非遗传因素至关重要。