Rabe-Jabłońska J
II Kliniki Psychiatrycznej Katedry Psychiatrii AM w Lodzi.
Psychiatr Pol. 1998 Mar-Apr;32(2):143-53.
This work presents results of a retrospective and prospective research of 15 persons with a double diagnosis: body dysmorphic disorder, and delusional disorder, somatic type. It was established that these disorders starting in adolescence, occurred in persons who earlier had traits of avoidant and obsessive-compulsive personality or social phobia. In most subjects with dysmorphophobia there was comorbidity of dysthymia or major depression. An improvement in the state of these patients, most often after implementation of complex therapeutic measures: psychotherapy as well as pharmacotherapy with neuroleptic and SSRI's or clomipramine has to do with withdrawal of delusions, whereas the symptoms of body dysmorphic disorder usually last for years. In some patients delusional disorders had a tendency to reoccur or to be chronic, and lead to a considerable impairment of social functioning.
这项研究呈现了对15名患有双重诊断(身体变形障碍和躯体型妄想障碍)患者的回顾性和前瞻性研究结果。研究发现,这些始于青春期的疾病发生在早期具有回避型、强迫型人格特质或社交恐惧症的人群中。在大多数患有畸形恐惧症的受试者中,存在心境恶劣或重度抑郁的共病情况。这些患者状况的改善,多数是在实施综合治疗措施(心理治疗以及使用抗精神病药物、选择性5-羟色胺再摄取抑制剂或氯米帕明进行药物治疗)之后,这与妄想的消除有关,而身体变形障碍的症状通常会持续数年。在一些患者中,妄想障碍有复发或慢性化的倾向,并导致相当程度的社会功能损害。