Wang L, Zhou X, Du X
Obstertric and Gynecologic Hospital of Shanghai Medical University.
Zhonghua Fu Chan Ke Za Zhi. 1997 Oct;32(10):605-8.
To investigate the relationship between the pathologic features of the uninvolved endometrium and prognosis in postmenopausal endometrial carcinoma.
The clinicopathologic features of 204 cases of endometrial carcinoma were analyzed retrospectively, according to the proliferative and atrophic uninvolved endometrium, a long term follow-up was done.
The patients with proliferative uninvolved endometrium (PUE) were more much related with the clinical risk factors than those of atrophic uninvolved endometrium (AUE) (P < 0.001). AUE cases had more virulent types of nonendometrial carcinoma than those of PUE (27% vs 5.5%, P < 0.001), and had much worse grade, much deeper myometrial invasion and much vascular invasion (P < 0.001). The overall 5-year survival rate was 96.7% in the PUE cases and 86.2% in the AUE cases (P < 0.001).
The histopathologic types of the uninvolved endometrium were related to the prognosis of the patients with endometrial carcinoma. The patients with proliferative uninvolved endometrium had better prognosis than those with atrophic uninvolved endometrium.
探讨绝经后子宫内膜癌未受累子宫内膜的病理特征与预后之间的关系。
回顾性分析204例子宫内膜癌的临床病理特征，根据未受累子宫内膜的增殖性和萎缩性进行长期随访。
增殖性未受累子宫内膜（PUE）患者比萎缩性未受累子宫内膜（AUE）患者与临床危险因素的相关性更强（P < 0.001）。AUE病例中非子宫内膜癌的恶性类型比PUE病例更多（27%对5.5%，P < 0.001），且分级更差、肌层浸润更深、血管浸润更严重（P < 0.001）。PUE病例的5年总生存率为96.7%，AUE病例为86.2%（P < 0.001）。
未受累子宫内膜的组织病理学类型与子宫内膜癌患者的预后相关。增殖性未受累子宫内膜患者的预后优于萎缩性未受累子宫内膜患者。
