Pinelli L, Mormile R, Gonfiantini E, Busato A, Kaufmann P, Piccoli R, Chiarelli F
Department of Paediatrics, Verona University Hospital, Italy.
J Pediatr Endocrinol Metab. 1998 Apr;11 Suppl 2:335-46.
A diet in line with RDAs is seldom achieved by IDDM patients. High post-prandial glucose levels are often attributed to food excess rather than to inadequate insulin doses. Lower dietary CHO with greater fat (in particular SFA) and protein are progressively scheduled instead of increasing insulin units. We studied 194 IDDM patients (1-23 yr) on a diet conforming to RDAs with a restriction of sucrose and without a quantitative approach and exchange lists of food for one year. The diet consisted of a high intake of starchy foods and vegetables and a restricted amount of animal products. HbA1c mean values of the year were used as an indicator of metabolic control. The mean daily insulin dose was 0.53 U/kg in patients with diabetes duration (DD) < 2 yr and 0.81 U/kg in those with DD > 2 yr. Mean annual HbA1c was 7.1 +/- 0.9%. The prevalence of obesity was low (5.7%). Adolescent females were more obese than males. A dietary approach in line with RDA requirements, that may help prevent any complications related to an inappropriate diet pattern, coupled with a dynamic insulin adjustment, is the first-line intervention to prevent complications in IDDM patients.
1型糖尿病患者很少能遵循推荐膳食摄入量(RDA)饮食。餐后高血糖水平通常归因于食物摄入过量,而非胰岛素剂量不足。逐渐安排较低的膳食碳水化合物(CHO),搭配更多脂肪(尤其是饱和脂肪酸[SFA])和蛋白质,而不是增加胰岛素单位。我们对194名1至23岁的1型糖尿病患者进行了为期一年的研究,其饮食符合RDA,限制蔗糖摄入,且没有定量方法和食物交换表。该饮食包括大量摄入淀粉类食物和蔬菜,以及少量动物产品。以该年度的糖化血红蛋白(HbA1c)平均值作为代谢控制的指标。糖尿病病程(DD)<2年的患者平均每日胰岛素剂量为0.53 U/kg,DD>2年的患者为0.81 U/kg。年平均HbA1c为7.1±0.9%。肥胖患病率较低(5.7%)。青春期女性比男性更肥胖。符合RDA要求的饮食方法,可能有助于预防与不适当饮食模式相关的任何并发症,再加上动态胰岛素调整,是预防1型糖尿病患者并发症的一线干预措施。