Baumgartner C, Lindinger G, Lurger S, Aull S, Bacher J, Leutmezer F, Olbrich A, Pataraia E, Serles W, Deecke L
Universitätsklinik für Neurologie, Wien.
Wien Med Wochenschr. 1998;148(1-2):2-8.
Prolonged video-EEG-monitoring facilitates a correlation of clinical seizure semiology and corresponding EEG changes. Indications for prolonged video-EEG-monitoring comprise differential diagnosis of epileptic and psychogenic seizures, correct classification of epileptic syndromes and presurgical evaluation of patients with medically refractory focal epilepsies. 6000 patients in Austria would benefit from epilepsy surgery with an additional 150 bis 200 new patients appearing each year. Presurgical evaluation consists of a non-invasive Phase I and an invasive Phase II. During Phase I each patient is evaluated with a prolonged video-EEG-monitoring with scalp-EEG, a MRI-scan, a SPECT- and/or PET-scan, a neuropsychological evaluation and a Wada-test. If the epileptogenic zone cannot be localized adequately with these methods, invasive electrophysiological techniques with intracranial (epidural peg-electrodes, foramen-ovale electrodes, subdural strip or grid electrodes) or intracerebral electrodes (stereotaxically implanted depth electrodes) have to be applied. Epilepsy surgery renders 70 to 80% of patients seizure free and thus can regarded an effective and safe treatment option for patients with medically refractory focal epilepsies.
长时间视频脑电图监测有助于临床癫痫发作症状学与相应脑电图变化的关联。长时间视频脑电图监测的适应证包括癫痫性发作与精神性发作的鉴别诊断、癫痫综合征的正确分类以及药物难治性局灶性癫痫患者的术前评估。奥地利有6000名患者将从癫痫手术中受益,每年还有150至200名新患者出现。术前评估包括非侵入性的第一阶段和侵入性的第二阶段。在第一阶段,对每位患者进行长时间视频脑电图监测(头皮脑电图)、磁共振成像扫描、单光子发射计算机断层扫描和/或正电子发射断层扫描、神经心理学评估以及韦达试验。如果通过这些方法不能充分定位致痫区,则必须应用颅内(硬膜外针电极、卵圆孔电极、硬膜下条状或栅格电极)或脑内电极(立体定向植入深度电极)的侵入性电生理技术。癫痫手术可使70%至80%的患者无癫痫发作,因此可被视为药物难治性局灶性癫痫患者的一种有效且安全的治疗选择。