子宫动脉多普勒检查在慢性高血压孕妇中的作用。

Role of uterine artery Doppler investigation in pregnant women with chronic hypertension.

作者信息

Frusca T, Soregaroli M, Zanelli S, Danti L, Guandalini F, Valcamonico A

机构信息

Department of Obstetrics and Gynecology, University of Brescia, Italy.

出版信息

Eur J Obstet Gynecol Reprod Biol. 1998 Jul;79(1):47-50. doi: 10.1016/s0301-2115(98)00045-1.

DOI:10.1016/s0301-2115(98)00045-1

PMID:9643403

Abstract

OBJECTIVE

To evaluate the role of uterine artery Doppler investigation in predicting perinatal outcome of patients with chronic hypertension.

STUDY DESIGN

Uterine artery velocimetry was investigated at 24 weeks gestation in 78 chronic hypertensive pregnant women by means of color Doppler. The resistance index (RI) and the presence of a diastolic notch were recorded and related to the development of superimposed preeclampsia (SPE), pregnancy aggravated hypertension (PAH). and intrauterine growth retardation (IUGR).

RESULTS

There were more pregnancy complications in the 25 patients with abnormal RI, compared with the 53 women with normal RI (SPE 12% vs. 0%, PAH 36% vs. 7% and IUGR 52% vs. 2%; P<0.01), and more in women with a bilateral diastolic notch compared with those without (SPE 23% vs. 0, PAH 54% vs. 4%, IUGR 85% vs. 2%; P<0.0001), while no differences were detected in those with only a unilateral notch, except for PAH (27% vs. 4%; P<0.01).

CONCLUSION

Uterine artery Doppler velocimetry identifies a subgroup of chronic hypertensive patients with a high frequency of pregnancy complications.

摘要

目的

评估子宫动脉多普勒检查在预测慢性高血压患者围产期结局中的作用。

研究设计

采用彩色多普勒对78例慢性高血压孕妇在妊娠24周时进行子宫动脉测速。记录阻力指数（RI）和舒张期切迹的情况，并将其与并发子痫前期（SPE）、妊娠加重高血压（PAH）及胎儿宫内生长受限（IUGR）的发生情况相关联。

结果

与53例RI正常的女性相比，25例RI异常的患者妊娠并发症更多（SPE分别为12%对0%，PAH分别为36%对7%，IUGR分别为52%对2%；P<0.01）；与无双侧舒张期切迹的女性相比，有双侧舒张期切迹的女性并发症更多（SPE分别为23%对0，PAH分别为54%对4%，IUGR分别为85%对2%；P<0.0001），而仅有单侧切迹的患者中，除PAH外（分别为27%对4%；P<0.01）未检测到差异。