File S E, Scott E M
Dev Psychobiol. 1976 Mar;9(2):97-107. doi: 10.1002/dev.420090202.
The acquisition and retention of habituation to air-puff was studied in rats on Days 1-19 postpartum. Animals of all ages demonstrated habituation but the rate of habituation varied with age: slower on each successive day from Day 1 to Day 8, but thereafter more rapid on each successive day. This peak of elicited responding is discussed in relation to the peak of spontaneous activity at Day 16 and to the pattern of neural development, including changes in acetylcholinesterase, norepinephrine, and serotonin, measured during the preweaning period. All ages showed 30-min retention of habituation, with 60-min retention developing after the 1st week. No evidence of 24-hr retention appeared at any age.
在产后第1至19天对大鼠进行了对气吹刺激的习惯化习得和保持的研究。所有年龄段的动物都表现出习惯化，但习惯化的速度随年龄而异：从第1天到第8天，每天的习惯化速度都较慢，但此后每天的习惯化速度更快。结合第16天的自发活动峰值以及断奶前测量的神经发育模式，包括乙酰胆碱酯酶、去甲肾上腺素和血清素的变化，对这种诱发反应的峰值进行了讨论。所有年龄段的动物在30分钟内都保持了习惯化，在第1周后发展为60分钟的保持。在任何年龄段都没有出现24小时保持的证据。
