体外培养的杜氏利什曼原虫前鞭毛体中脂磷壁酸聚糖（LPG）和动基体膜蛋白（KMP）-11的表达降低。
Reduced expression of lipophosphoglycan (LPG) and kinetoplastid membrane protein (KMP)-11 in Leishmania donovani promastigotes in axenic culture.
作者信息
Mukhopadhyay S, Sen P, Majumder H K, Roy S
机构信息
Department of Immunology, Indian Institute of Chemical Biology, Calcutta.
出版信息
J Parasitol. 1998 Jun;84(3):644-7.
PMID:9645879
Abstract
The expression of surface lipophosphoglycan (LPG) and the lipophosphoglycan-associated kinetoplastid membrane protein (KMP)-11 was studied in the strain AG83 of Leishmania donovani in axenic culture. The expression of LPG and KMP-11 decreased along with parasite virulence as a function of the time of the subculture.
摘要
在体外培养的杜氏利什曼原虫AG83株中，研究了表面脂磷壁酸聚糖（LPG）和脂磷壁酸聚糖相关动基体膜蛋白（KMP）-11的表达情况。随着继代培养时间的延长，LPG和KMP-11的表达随寄生虫毒力的降低而减少。
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