Disseminated infection with Saccharomyces kluyveri in a patient with AIDS.

A 47-year-old man with acquired immune deficiency syndrome was found to have disseminated Saccharomyces kluyveri infection. The yeast was isolated from blood and cerebro-spinal fluid. An autopsy revealed the presence of the microorganism in many organs including liver, kidneys, pancreas, spleen, lung, and brain. The case confirms a potential pathogenicity of yeasts of the genus Saccharomyces in patients with profound immune deficiency, especially in advanced HIV infection.