Santiso Gabriela, Chediak Viviana, Maiolo Elena, Mujica María T, San Juan Jorge, Arechavala Alicia, Negroni Ricardo
Unidad Micología, Hospital de Infecciosas F.J.Muñiz.
Rev Argent Microbiol. 2011 Oct-Dec;43(4):268-72. doi: 10.1590/S0325-75412011000400006.
The first case observed in Argentina of AIDS-related human penicillosis is herein presented. The patient was a six- teen year-old young man coming from a rural area of southern China. He was admitted at the F. J. Muñiz Hospital of Buenos Aires city with severe pneumonia and adult respiratory distress. Penicillium marneffei was isolated from bronchoalveolar lavage fuid and was microscopically observed in a skin cytodiagnosis. P. marneffei identification was confirmed by rRNA amplification and its phenotypic characteristics. The patient suffered an advanced HIV infection and also presented several AIDS-related diseases due to CMV, nosocomial bacterial infections and Pneumocystis jirovecii which led to a fatal outcome.
本文报告了在阿根廷观察到的首例与艾滋病相关的马尔尼菲青霉病病例。患者是一名来自中国南方农村地区的16岁青年男子。他因严重肺炎和成人呼吸窘迫入住布宜诺斯艾利斯市的F. J. 穆尼兹医院。从支气管肺泡灌洗液中分离出马尔尼菲青霉，并在皮肤细胞诊断中通过显微镜观察到。通过rRNA扩增及其表型特征确认了马尔尼菲青霉的鉴定。该患者患有晚期HIV感染，还出现了几种与艾滋病相关的疾病，包括巨细胞病毒感染、医院获得性细菌感染和耶氏肺孢子菌感染，最终导致死亡。
