Huber S, Delorme S, Zuna I
Abteilung für Radiologie, KH Lainz, Wien.
Radiologe. 1998 May;38(5):390-3. doi: 10.1007/s001170050369.
Findings in previous investigations have indicated that contrast-enhanced colour Doppler can be used to improve the demonstration of characteristic features of neovascularization in malignancies. However, the quantification of the increase in colour Doppler signals after Levovist in the cited study relied only on descriptive criteria defined by the investigator, resulting in a subjective scoring system. A computer-assisted method for quantitative analysis of colour pixel density is a novel approach for objective assessment of colour Doppler signal after contrast media administration. After microbubble contrast medium injection in 47 patients, carcinomas and benign lesions behaved differently regarding degree, onset and duration of Doppler enhancement. However, the high interindividual variability and the temporal variations of the Doppler signal still limit the value of these criteria for prospective diagnosis. Rapid image-acquisition techniques are needed in order to apply the necessary mathematical processing before the contrast kinetics can be used for diagnostic purposes.
先前的研究结果表明，对比增强彩色多普勒可用于改善恶性肿瘤新生血管特征的显示。然而，在上述研究中，对注射Levovist后彩色多普勒信号增加的量化仅依赖于研究者定义的描述性标准，从而形成了一个主观评分系统。一种用于彩色像素密度定量分析的计算机辅助方法是在注射造影剂后客观评估彩色多普勒信号的新途径。对47例患者注射微泡造影剂后，癌灶和良性病变在多普勒增强的程度、起始时间和持续时间方面表现不同。然而，多普勒信号的个体间高度变异性和时间变化仍然限制了这些标准在前瞻性诊断中的价值。为了在对比剂动力学用于诊断目的之前进行必要的数学处理，需要快速图像采集技术。
