International Union of Pharmacology. XVIII. Nomenclature of receptors for vasoactive intestinal peptide and pituitary adenylate cyclase-activating polypeptide.
作者信息
Harmar A J, Arimura A, Gozes I, Journot L, Laburthe M, Pisegna J R, Rawlings S R, Robberecht P, Said S I, Sreedharan S P, Wank S A, Waschek J A
机构信息
MRC Brain Metabolism Unit, Royal Edinburgh Hospital, Scotland, UK.
出版信息
Pharmacol Rev. 1998 Jun;50(2):265-70.
Abstract
摘要
相似文献
1
2
Properties of the pituitary adenylate cyclase-activating polypeptide I and II receptors, vasoactive intestinal peptide1, and chimeric amino-terminal pituitary adenylate cyclase-activating polypeptide/vasoactive intestinal peptide1 receptors: evidence for multiple receptor states.垂体腺苷酸环化酶激活多肽I和II受体、血管活性肠肽1以及嵌合氨基末端垂体腺苷酸环化酶激活多肽/血管活性肠肽1受体的特性：多种受体状态的证据
Mol Pharmacol. 1996 Dec;50(6):1596-604.
3
A cloned frog vasoactive intestinal polypeptide/pituitary adenylate cyclase-activating polypeptide receptor exhibits pharmacological and tissue distribution characteristics of both VPAC1 and VPAC2 receptors in mammals.克隆的蛙血管活性肠肽/垂体腺苷酸环化酶激活肽受体具有哺乳动物中VPAC1和VPAC2受体的药理学及组织分布特征。
Endocrinology. 1999 Mar;140(3):1285-93. doi: 10.1210/endo.140.3.6576.
4
Pharmacology and functions of receptors for vasoactive intestinal peptide and pituitary adenylate cyclase-activating polypeptide: IUPHAR review 1.血管活性肠肽和垂体腺苷酸环化酶激活肽受体的药理学和功能：国际药理学联合会评论 1。
Br J Pharmacol. 2012 May;166(1):4-17. doi: 10.1111/j.1476-5381.2012.01871.x.
5
Heterogeneity of pituitary adenylate cyclase-activating polypeptide and vasoactive intestinal polypeptide receptors in rat intrinsic cardiac neurons.大鼠心脏固有神经元中垂体腺苷酸环化酶激活多肽和血管活性肠肽受体的异质性
Neurosci Lett. 2002 Aug 2;328(1):45-9. doi: 10.1016/s0304-3940(02)00445-7.
6
Pituitary adenylate cyclase-activating polypeptide/vasoactive intestinal polypeptide receptor subtypes are differently expressed in rat transplanted pituitary tumours (SMtTW) and in the normal gland.垂体腺苷酸环化酶激活多肽/血管活性肠肽受体亚型在大鼠移植性垂体肿瘤（SMtTW）和正常腺体内的表达存在差异。
J Mol Endocrinol. 1996 Jun;16(3):239-48. doi: 10.1677/jme.0.0160239.
7
Pituitary adenylate cyclase-activating polypeptide receptors mediating insulin secretion in rodent pancreatic islets are coupled to adenylate cyclase but not to PLC.介导啮齿动物胰岛胰岛素分泌的垂体腺苷酸环化酶激活多肽受体与腺苷酸环化酶偶联，但不与磷脂酶C偶联。
Endocrinology. 2002 Apr;143(4):1253-9. doi: 10.1210/endo.143.4.8739.
8
Characterization of vasoactive intestinal peptide/pituitary adenylate cyclase-activating polypeptide receptors in chick cerebral cortex.鸡大脑皮层中血管活性肠肽/垂体腺苷酸环化酶激活多肽受体的特性分析
J Mol Neurosci. 2003 Apr;20(2):153-62. doi: 10.1385/JMN:20:2:153.
9
Characterization of vasoactive intestinal peptide/pituitary adenylate cyclase-activating peptide receptors in human benign hyperplastic prostate.人良性增生前列腺中血管活性肠肽/垂体腺苷酸环化酶激活肽受体的特征分析
Endocrinology. 1996 Jul;137(7):2815-22. doi: 10.1210/endo.137.7.8770902.
10
Additional signals from VPAC/PAC family receptors.来自VPAC/PAC家族受体的其他信号。
Biochem Soc Trans. 2002 Aug;30(4):441-6. doi: 10.1042/bst0300441.
引用本文的文献
1
PACAP38-induced migraine attacks are independent of CGRP signaling: a randomized controlled trial.促肾上腺皮质激素释放激素相关肽38诱导的偏头痛发作与降钙素基因相关肽信号传导无关：一项随机对照试验。
J Headache Pain. 2025 Apr 14;26(1):79. doi: 10.1186/s10194-025-02022-2.
2
Pituitary adenylate cyclase-activating polypeptide signalling as a therapeutic target in migraine.垂体腺苷酸环化酶激活肽信号作为偏头痛的治疗靶点。
Nat Rev Neurol. 2024 Nov;20(11):660-670. doi: 10.1038/s41582-024-01011-4. Epub 2024 Sep 10.
3
Pituitary cyclase-activating polypeptide targeted treatments for the treatment of primary headache disorders.针对原发性头痛疾病的垂体腺苷酸环化酶激活肽靶向治疗。
Ann Clin Transl Neurol. 2024 Jul;11(7):1654-1668. doi: 10.1002/acn3.52119. Epub 2024 Jun 18.
4
PAC1 deficiency reduces chondrogenesis in atherosclerotic lesions of hypercholesterolemic ApoE-deficient mice.PAC1 缺乏会减少高脂血症 ApoE 缺陷小鼠动脉粥样硬化病变中的软骨生成。
BMC Cardiovasc Disord. 2023 Nov 18;23(1):566. doi: 10.1186/s12872-023-03600-5.
5
Neuronal diversity of neuropeptide signaling, including galanin, in the mouse locus coeruleus.蓝斑核中神经肽信号的神经元多样性，包括甘丙肽。
Proc Natl Acad Sci U S A. 2023 Aug;120(31):e2222095120. doi: 10.1073/pnas.2222095120. Epub 2023 Jul 24.
6
Gene Expression Analysis Links Autocrine Vasoactive Intestinal Peptide and ZEB1 in Gastrointestinal Cancers.基因表达分析揭示胃肠癌中自分泌血管活性肠肽与ZEB1之间的联系
Cancers (Basel). 2023 Jun 22;15(13):3284. doi: 10.3390/cancers15133284.
7
Regulation of UV-B-Induced Inflammatory Mediators by Activity-Dependent Neuroprotective Protein (ADNP)-Derived Peptide (NAP) in Corneal Epithelium.活性依赖性神经保护蛋白（ADNP）衍生肽（NAP）调控 UV-B 诱导的角膜上皮炎症介质。
Int J Mol Sci. 2023 Apr 7;24(8):6895. doi: 10.3390/ijms24086895.
8
Activation of the PACAP/PAC1 Signaling Pathway Accelerates the Repair of Impaired Spatial Memory Caused by an Ultradian Light Cycle.激活 PACAP/PAC1 信号通路加速超昼夜节律光周期引起的受损空间记忆的修复。
ASN Neuro. 2023 Jan-Dec;15:17590914231169140. doi: 10.1177/17590914231169140.
9
Timed exercise stabilizes behavioral rhythms but not molecular programs in the brain's suprachiasmatic clock.定时运动可稳定行为节律，但对大脑视交叉上核生物钟中的分子程序却无此作用。
iScience. 2023 Jan 18;26(2):106002. doi: 10.1016/j.isci.2023.106002. eCollection 2023 Feb 17.
10
PACAP-PAC1 receptor inhibition is effective in opioid induced hyperalgesia and medication overuse headache models.垂体腺苷酸环化酶激活肽 - PAC1受体抑制在阿片类药物诱导的痛觉过敏和药物滥用性头痛模型中有效。
iScience. 2023 Jan 10;26(2):105950. doi: 10.1016/j.isci.2023.105950. eCollection 2023 Feb 17.
本文引用的文献
1
Vasoactive intestinal polypeptide: biologic role in health and disease.血管活性肠肽：在健康与疾病中的生物学作用
Trends Endocrinol Metab. 1991 May-Jun;2(3):107-12. doi: 10.1016/s1043-2760(05)80006-2.
2
In vitro properties of a high affinity selective antagonist of the VIP1 receptor.血管活性肠肽1型受体高亲和力选择性拮抗剂的体外特性
Peptides. 1997;18(10):1555-60. doi: 10.1016/s0196-9781(97)00230-1.
3
Autoradiographic visualization of the receptor subclasses for vasoactive intestinal polypeptide (VIP) in rat brain.大鼠脑中血管活性肠肽（VIP）受体亚类的放射自显影可视化。
Peptides. 1997;18(10):1547-54. doi: 10.1016/s0196-9781(97)00229-5.
4
Development of high affinity selective VIP1 receptor agonists.高亲和力选择性VIP1受体激动剂的研发。
Peptides. 1997;18(10):1539-45. doi: 10.1016/s0196-9781(97)00228-3.
5
Evidence for roles of vasoactive intestinal polypeptide (VIP) and pituitary adenylate cyclase activating polypeptide (PACAP) receptors in modulating the responses of rat dorsal horn neurons to sensory inputs.血管活性肠肽（VIP）和垂体腺苷酸环化酶激活肽（PACAP）受体在调节大鼠背角神经元对感觉输入反应中的作用证据。
Neuropeptides. 1997 Apr;31(2):175-85. doi: 10.1016/s0143-4179(97)90087-1.
6
Novel cyclic peptide agonist of high potency and selectivity for the type II vasoactive intestinal peptide receptor.对II型血管活性肠肽受体具有高效力和选择性的新型环肽激动剂。
J Pharmacol Exp Ther. 1997 May;281(2):629-33.
7
The long-acting vasoactive intestinal polypeptide agonist RO 25-1553 is highly selective of the VIP2 receptor subclass.长效血管活性肠肽激动剂RO 25 - 1553对VIP2受体亚类具有高度选择性。
Peptides. 1997;18(3):403-8. doi: 10.1016/s0196-9781(96)00322-1.
8
Pituitary adenylate cyclase-activating peptide (PACAP) in the retinohypothalamic tract: a potential daytime regulator of the biological clock.视网膜下丘脑束中的垂体腺苷酸环化酶激活肽（PACAP）：生物钟潜在的日间调节因子。
J Neurosci. 1997 Apr 1;17(7):2637-44. doi: 10.1523/JNEUROSCI.17-07-02637.1997.
9
Maxadilan, the vasodilator from sand flies, is a specific pituitary adenylate cyclase activating peptide type I receptor agonist.来自沙蝇的血管舒张肽——大昔蓝，是一种特异性的Ⅰ型垂体腺苷酸环化酶激活肽受体激动剂。
J Biol Chem. 1997 Jan 10;272(2):966-70. doi: 10.1074/jbc.272.2.966.
10
Vasoactive intestinal peptide and nitric oxide: divergent roles in relation to tissue injury.血管活性肠肽与一氧化氮：在组织损伤方面的不同作用。
Ann N Y Acad Sci. 1996 Dec 26;805:379-87; discussion 387-8. doi: 10.1111/j.1749-6632.1996.tb17498.x.
Zotero 插件