Sandoval C, Stringel G, Ozkaynak M F, Tugal O, Jayabose S
Department of Pediatrics, New York Medical College, Valhalla 10595, USA.
Cancer Genet Cytogenet. 1998 Jul 1;104(1):61-5. doi: 10.1016/s0165-4608(97)00433-0.
Isochromosome 7q is a nonrandom cytogenetic abnormality in Wilms tumor. Two notable cases are described: (1) a case of bilateral Wilms tumor in which only the left-sided tumor contained isochromosome 7q and (2) a case of left-sided Wilms tumor in which the tumor contained isochromosome 7q, in addition to four other chromosomal abnormalities associated with Wilms tumor.