Takemori M, Nishimura R, Yamasaki M, Kawabe Y, Hasegawa K
Department of Obstetrics and Gynecology, Hyogo Medical Center for Adults, Akashi, Japan.
Gynecol Oncol. 1998 Jun;69(3):260-3. doi: 10.1006/gyno.1998.5006.
We report the case of a 41-year-old woman with ovarian mixed germ cell tumor which was composed of polyembryoma and immature teratoma and who had high serum levels of alpha-fetoprotein (AFP) and human chorionic gonadotropin (hCG). By immunohistochemical methods, AFP was found in yolk sac cells of the embryoid bodies and immature hepatoid tissues, and hCG was found in giant syncytiotrophoblastic cells. She was treated with surgery followed by cisplatin-based combination chemotherapy. She is well, and her serum levels of AFP and hCG have not been elevated for more than 4 years after the treatment.
我们报告了一例41岁患有卵巢混合性生殖细胞肿瘤的女性病例，该肿瘤由多胚瘤和未成熟畸胎瘤组成，且血清甲胎蛋白（AFP）和人绒毛膜促性腺激素（hCG）水平升高。通过免疫组织化学方法，在胚体的卵黄囊细胞和未成熟肝样组织中发现了AFP，在巨大合体滋养层细胞中发现了hCG。她接受了手术治疗，随后进行了以顺铂为基础的联合化疗。她目前状况良好，治疗后4年多来血清AFP和hCG水平一直未升高。
