Alpha-fetoprotein producing pulmonary blastoma in a patient with systemic sclerosis: pathogenetic analysis.
作者信息
Kasuga I, Miyamoto D, Ichinose Y, Chimangul W, Minemura K, Utsumi K, Yonemaru M, Serizawa H, Ebihara Y, Toyama K
机构信息
First Dept of Internal Medicine, Tokyo Medical College Hospital, Japan.
出版信息
Eur Respir J. 1998 May;11(5):1185-7. doi: 10.1183/09031936.98.11051185.
PMID:9648976
Abstract
We describe a rare case of pulmonary blastoma complicated with systemic sclerosis. The serum alpha-fetoprotein level was elevated at presentation and the biopsied tumour stained positively against anti-alpha-fetoprotein antibody. The alpha-fetoprotein produced autonomously by tumour cells was of yolk-sac origin. Although the pathogenesis of pulmonary blastoma has not been clarified, we suggest that this pulmonary blastoma is a type of yolk-sac tumour.
摘要
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