Dokos S, Lovell N H, Celler B G
Department of Physiology, School of Medicine, University of Auckland, New Zealand.
J Theor Biol. 1998 Jun 7;192(3):265-74. doi: 10.1006/jtbi.1997.0619.
Mathematical models of ion currents in pacemaker cells of the heart and their associated modulation by vagal stimulation have provided numerous insights into the ionic mechanisms underlying parasympathetic control of heart rate. In this article, ionic models described in the literature are reviewed and compared, with a view to examining their effectiveness in reproducing known chronotropic responses to vagal stimulation.
心脏起搏细胞中离子电流的数学模型及其通过迷走神经刺激的相关调节，为深入了解副交感神经控制心率的离子机制提供了诸多见解。在本文中，将对文献中描述的离子模型进行综述和比较，以考察它们在再现已知的迷走神经刺激变时反应方面的有效性。
