Pospísilová A
II. dermatovenerologická klinika FNsP, Brno-Bohunice.
Cas Lek Cesk. 1998 May 4;137(9):264-6.
Current methods of topical treatment of leg ulcers are reviewed. Leg ulcers are chronic wounds in a trophically altered tissue that affects the healing capacity. Complete healing requires prolonged and rather expensive treatment and the patient is often disabled during this period. The conventional methods of treatment of leg ulcers, including various compresses, ointments, pastes and other topical drugs, that may possess a considerable sensitizing potential, are to an increasing extent replaced by updated therapy consisting in the use of a new generation of dressings. The latter include a number of materials that have been developed on the basis of recent knowledge of wound healing, such as hydrogels, hydrocolloids, xerogels, hydropolymer dressings, polyurethane foam sheets, alginate dressings, and non-adherent, non-woven cloth impregnated with silver and activated charcoal. The selection of the available materials must depend on the character and stage of the healing process. Each group of dressings exerts specific effects and none of them can recommended generally for the treatment of any types of ulceration. A brief survey of indications is given for each group to avoid their abuse.
本文综述了目前治疗腿部溃疡的局部治疗方法。腿部溃疡是发生在营养状况改变的组织中的慢性伤口，会影响愈合能力。完全愈合需要长期且相当昂贵的治疗，在此期间患者往往行动不便。传统的腿部溃疡治疗方法，包括各种敷料、药膏、糊剂和其他局部用药，可能具有相当大的致敏潜力，正越来越多地被采用新一代敷料的更新疗法所取代。后者包括一些基于近期伤口愈合知识开发的材料，如水凝胶、水胶体、干凝胶、水聚合物敷料、聚氨酯泡沫片、藻酸盐敷料，以及浸渍了银和活性炭的非粘性无纺布。可用材料的选择必须取决于愈合过程的特点和阶段。每组敷料都有特定的作用，没有一种敷料能普遍推荐用于治疗任何类型的溃疡。为避免滥用，对每组敷料的适应症进行了简要概述。
