Ohno R
Department of Medicine III, Hamamatsu University School of Medicine, Japan.
Int J Hematol. 1998 Apr;67(3):213-9.
Leukemia is an uncommon disease. In order to conduct a scientific clinical study, a large number of patients is required for reliable statistical analysis, and therefore, multicenter cooperative study is indispensable in leukemia. Not only in the field of hematology/oncology but also in other fields of clinical medicine, well-functioning clinical study groups are still rare in Japan. In this review, the reason why the organization of multicenter cooperative study groups is difficult in Japan is analyzed. Then the 10-year experience of a self-supporting and quite successful cooperative study group, the Japan Adult Leukemia Study Group, is reviewed. Finally, the next steps for the Group and the way it might be successfully led are discussed.
白血病是一种罕见疾病。为了开展科学的临床研究，需要大量患者才能进行可靠的统计分析，因此，多中心合作研究在白血病研究中不可或缺。不仅在血液学/肿瘤学领域，在临床医学的其他领域，日本运作良好的临床研究团队仍然很少。在这篇综述中，分析了日本难以组建多中心合作研究团队的原因。然后回顾了一个自筹资金且相当成功的合作研究团队——日本成人白血病研究组的十年经验。最后，讨论了该研究组的下一步计划以及可能成功引领其发展的方式。
