Aleryani S, Huorka M, Payer J, Duris I, Ondrejka P, Kratochvíl'ová H
I. interná klinika FN, Bratislava.
Vnitr Lek. 1997 Nov;43(11):733-7.
The authors compared in seven patients with acute pancreatitis the levels of endogenous somatostatin, insulin and C-peptide to assess their mutual correlation and relation to the development of the disease and serum amalyse levels. The results were compared with values recorded in 11 healthy volunteers. The levels of endogenous somatostatin were in patients with acute pancreatitis significantly higher (p < 0.05) than in the control group. The authors found an inverse relationship between the somatostatin and amylase level (correlation coefficient 0.75). They did not observe a significant correlation between somatostatin and insulin levels nor between somatostatin and C-peptide levels. The elevated somatostatin level may be due to the counteregulatory reaction during secretion, stimulated by endogenous or exogenous factors (cholecystokinin, alcohol, food).
作者比较了7例急性胰腺炎患者体内内源性生长抑素、胰岛素和C肽的水平，以评估它们之间的相互关系以及与疾病发展和血清淀粉酶水平的关系。将结果与11名健康志愿者记录的值进行了比较。急性胰腺炎患者体内内源性生长抑素水平显著高于对照组（p < 0.05）。作者发现生长抑素与淀粉酶水平呈负相关（相关系数为0.75）。他们未观察到生长抑素与胰岛素水平之间以及生长抑素与C肽水平之间存在显著相关性。生长抑素水平升高可能是由于内源性或外源性因素（胆囊收缩素、酒精、食物）刺激分泌过程中的反调节反应所致。
