Renal colic and associated pyelorenal reflux as a cause of some diseases.

Renal colic always involves pelvic hypertension and severe urodynamic disturbances which result in fornical reflux, urine leakage to renal interstitial tissues, to tissues of the renal sinus, and sometimes to the retroperitoneal space. If the urinary tract is infected, renal colic may lead to acute pyelonephritis and generalized infection, as well as to bacteriemic shock. Of great importance in the origin of retroperitoneal fibrosis are fornical refluxes. Since renal colic is the most frequent cause of pyelorenal reflux, patients with renal colic should be promptly given appropriate treatment aimed at eliminating or at least lowering pelvic hypertension.