Johnston S D, Trouton T G, Wilson C
Department of Medicine, Institute of Clinical Science, Royal Victoria Hospital, Belfast.
Ulster Med J. 1998 May;67(1):19-24.
The risk of arterial embolism is well recognised following Direct Current Cardioversion (DCC) for atrial fibrillation although the use of prophylactic anticoagulation remains controversial.
To determine the risk of arterial embolism post-cardioversion and which factors predict successful cardioversion and maintenance of sinus rhythm.
A retrospective study was carried out of all cardioversions performed for atrial fibrillation and atrial flutter at the Waveney Hospital Ballymena, during 1989-1993. A review of medical records and electrocardiograms was carried out to assess demographic characteristics, co-existent diseases, anticoagulant status, echocardiographic features and characteristics of the arrhythmia. Embolic events in the six weeks post-cardioversion were noted.
The study included 157 cardioversions in 109 patients. The predominant arrhythmia was atrial fibrillation (n = 108, 69%). Three of 109 patients (2.7%) experienced embolic complications, none of whom had anticoagulation prior to the procedure. No risk factors for cerebro-vascular disease or significant valvular heart disease were present. Return to sinus rhythm was achieved in 143 (91%) procedures. Increasing coarseness of atrial fibrillation was associated with a non-significant trend towards successful restoration of sinus rhythm (p = 0.18). Recurrence of the original arrhythmia was predicted by an increase in coarseness of atrial fibrillation (p < 0.05).
These findings indicate that embolic complications can occur in patients undergoing DCC with normal echocardiographic dimensions, and that prophylactic anticoagulation should be considered in all patients. Coarseness of atrial fibrillation may be used as a guide to predict the chance of successful cardioversion and of the likelihood of maintaining sinus rhythm once this has been achieved.
直流电复律(DCC)治疗心房颤动后动脉栓塞的风险已得到充分认识,尽管预防性抗凝治疗的应用仍存在争议。
确定复律后动脉栓塞的风险以及哪些因素可预测复律成功和窦性心律的维持。
对1989 - 1993年期间在巴利米纳的瓦夫尼医院进行的所有心房颤动和心房扑动复律病例进行回顾性研究。查阅病历和心电图以评估人口统计学特征、并存疾病、抗凝状态、超声心动图特征及心律失常特点。记录复律后六周内的栓塞事件。
该研究纳入了109例患者的157次复律。主要心律失常为心房颤动(n = 108,69%)。109例患者中有3例(2.7%)发生栓塞并发症,这些患者在手术前均未进行抗凝治疗。不存在脑血管疾病或严重瓣膜性心脏病的危险因素。143例(91%)复律成功恢复窦性心律。心房颤动的粗化程度增加与窦性心律成功恢复的趋势无显著相关性(p = 0.18)。心房颤动粗化程度增加可预测原心律失常的复发(p < 0.05)。
这些发现表明,超声心动图尺寸正常的患者在进行直流电复律时可能发生栓塞并发症,所有患者均应考虑预防性抗凝治疗。心房颤动的粗化程度可作为预测复律成功机会以及复律成功后维持窦性心律可能性的指标。