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恶性软骨肿瘤的诊断成像

Diagnostic imaging of malignant cartilage tumors.

作者信息

Masciocchi C, Sparvoli L, Barile A

机构信息

Department of Radiology, University of L'Aquila, Hospital Santa Maria di Collemaggio, Italy.

出版信息

Eur J Radiol. 1998 May;27 Suppl 1:S86-90. doi: 10.1016/s0720-048x(98)00048-5.

Abstract

We compared the diagnostic capabilities of CT and MRI in the study of malignant cartilage tumors. Information about the characterization and the intra-/extraosseous spread of these lesions is of primary importance in the preoperative planning. Besides peripheral chondrosarcomas, arising from an osteochondroma and central chondrosarcomas, which are the most common malignant cartilaginous tumors, we also considered secondary, periosteal, dedifferentiated, clear cells and mesenchymal chondrosarcomas. Our study was performed using a standard MRI and CT protocol; in some cases, the examination was completed by the intravenous administration of a contrast agent. High contrast T2-weighted GE images can perfectly depict and differentiate the cartilage cap of an osteochondroma from the adjacent soft tissues. Evaluation of the growth of exostosis and of the thickness of its cap is essential in the assessement of malignant transformation. Both CT and MRI provide important information about peculiar aspects of the cartilaginous matrix such as the shape of calcifications-ossifications and lobulated growth, septa, septal enchancement and necrotic intratumoral areas, furthermore, CT perfectly shows the patterns of bone destruction. MRI should be considered as the most reliable imaging technique for the locoregional staging of malignant bone tumors thanks to its spatial and contrast resolution. CT plays a major role in the characterization of most bone tumors, especially those with a cartilaginous matrix.

摘要

我们比较了CT和MRI在恶性软骨肿瘤研究中的诊断能力。在术前规划中,了解这些病变的特征以及骨内/外扩散情况至关重要。除了起源于骨软骨瘤的外周型软骨肉瘤和最常见的恶性软骨肿瘤中央型软骨肉瘤外,我们还纳入了继发性、骨膜型、去分化型、透明细胞型和间叶型软骨肉瘤。我们的研究采用标准的MRI和CT方案;在某些情况下,通过静脉注射造影剂来完成检查。高对比度T2加权GE图像能够完美地描绘并区分骨软骨瘤的软骨帽与相邻软组织。评估外生骨疣的生长及其帽的厚度对于判断恶性转化至关重要。CT和MRI均能提供有关软骨基质特殊方面的重要信息,如钙化-骨化的形态、分叶状生长、间隔、间隔强化及瘤内坏死区域,此外,CT能完美显示骨质破坏的模式。由于其空间和对比度分辨率,MRI应被视为恶性骨肿瘤局部区域分期最可靠的成像技术。CT在大多数骨肿瘤的特征性诊断中发挥着重要作用,尤其是那些具有软骨基质的肿瘤。

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