Kamimura M, Tanabe N, Hojo M, Horiuchi T, Kudo K, Saitoh K
Pulmonology Department, International Medical Center of Japan, Tokyo.
Intern Med. 1998 May;37(5):463-6. doi: 10.2169/internalmedicine.37.463.
We report a case of T-cell-rich large B-cell lymphoma demonstrating sick sinus syndrome as a single initial symptom, followed by the retention of pericardial and pleural effusions. Intrapleural administration of interferon-alpha prevented reaccumulation of the pleural effusion for one and a half months, whereas systemic chemotherapy failed to control tumor growth in the skin and lymph nodes. The autopsy revealed involvement of the sinoatrial node of the heart by lymphoma cells.
我们报告一例富于T细胞的大B细胞淋巴瘤，其首发单一症状为病态窦房结综合征，随后出现心包和胸腔积液。胸腔内注射α干扰素使胸腔积液在一个半月内未再积聚，而全身化疗未能控制皮肤和淋巴结的肿瘤生长。尸检显示淋巴瘤细胞累及心脏窦房结。
