Bregman J
Department of Pediatrics, Evanston Northwestern Healthcare, Evanston Hospital, Illinois, USA.
Pediatr Clin North Am. 1998 Jun;45(3):673-90. doi: 10.1016/s0031-3955(05)70035-3.
Surfactant therapy has significantly reduced mortality, but not morbidity, in the very low birthweight (VLBW) infant. Questions persist as to the edge of viability, the allocation of health care resources for the VLBW infant, and whether or not we are improving survival at the cost of contributing more handicapped individuals to society. Since surfactant alone has not reduced morbidity, other medical and behavioral treatments are being studied that may help to optimize neurodevelopmental outcome in the VLBW infant.
表面活性剂疗法已显著降低了极低出生体重(VLBW)婴儿的死亡率,但并未降低其发病率。关于生存极限、为VLBW婴儿分配医疗保健资源以及我们是否是以让更多残障个体进入社会为代价来提高生存率等问题依然存在。由于仅使用表面活性剂并未降低发病率,目前正在研究其他医学和行为治疗方法,这些方法可能有助于优化VLBW婴儿的神经发育结局。