Edwards J S
Department of Zoology, University of Washington, Seattle 98195, USA.
Int J Dev Biol. 1998;42(3):471-3.
Sir Vincent Wigglesworth (1899-1994), a founder of the discipline of Insect Physiology, was a central figure in the emergence of the concept of postembryonic insect development as sequential polymorphism regulated by endocrine signals. At a time in mid-century when genetics and developmental physiology were severely compartmentalized, he made the conceptual linkage with the recognition that sequential polymorphism must have a genetic basis with gene activation regulated by internal signals.