Thomas N J, Carcillo J A
Department of Anesthesiology/Critical Care Medicine and Pediatrics, Children's Hospital of Pittsburgh, University of Pittsburgh Medical Center, PA 15213-2583, USA.
New Horiz. 1998 May;6(2):120-9.
Hypovolemic shock is a common disease treated in pediatric ICUs and emergency departments worldwide. A wide variety of etiologic factors may cause this disease, with the common net result of decreased intravascular volume leading to decreased venous return to the heart and decreased stroke volume. Inadequate perfusion results in impairment of delivery of nutrients and oxygen to vital end organs. With the advent of pediatric critical care and pediatric emergency medicine as specialties, deaths from hypovolemic shock have become increasingly rare in the United States. The physical signs of hypovolemic shock in children must be quickly recognized, and aggressive volume resuscitation must be administered before irreversible end-organ dysfunction occurs. This is best accomplished by large peripheral or central intravenous access, with intraosseous access an alternative option in the pediatric patient. The amount as well as the type of volume administered must be tailored for each individual patient, taking into account the amount of intravascular depletion and the disease state in which the shock has occurred. It is not uncommon for children to require large amounts of fluid for resuscitation, and close attention must be paid to children with fluid-refractory shock, who may require catecholamine and/or exogenous steroid support in combination with aggressive fluid resuscitation.
低血容量性休克是全球儿科重症监护病房和急诊科治疗的常见疾病。多种病因可导致该病,共同的最终结果是血管内容量减少,导致静脉回心血量减少和心输出量降低。灌注不足导致营养物质和氧气向重要终末器官的输送受损。随着儿科重症医学和儿科急诊医学作为专业领域的出现,在美国,低血容量性休克导致的死亡已越来越罕见。必须迅速识别儿童低血容量性休克的体征,并且在不可逆转的终末器官功能障碍发生之前进行积极的容量复苏。这最好通过大口径外周或中心静脉通路来完成,对于儿科患者,骨内通路是一种替代选择。补液的量和类型必须根据每个患者的情况进行调整,要考虑到血管内液体缺失的量以及发生休克的疾病状态。儿童复苏时需要大量液体的情况并不少见,对于难治性休克患儿必须密切关注,他们可能需要在积极补液的同时联合使用儿茶酚胺和/或外源性类固醇支持治疗。