Vayre P, Delavierre P, Duran M
J Chir (Paris). 1976 Jan;111(1):113-22.
From their experimental findings in 120 rabbits, the authors conclude that, at first, cholecystitis is usually an aseptic lesion and infection occurs only secondarily. In a large number of cases the initial physiopathological mechanism is that of inflammation which may be due to mechanical causes such as obstruction of the gall bladder siphon and vasomotor phenomena under autonomic control. The histological lesions and course are comparable to those observed in clinical medicine. The interest of this experimental study is to compare the pathology of acute cholecystitis with pancreatitis and Reilly's syndrome and Gregoire and Couvelaire's theory of visceral apoplexy.
根据他们在120只兔子身上的实验结果，作者得出结论：起初，胆囊炎通常是无菌性病变，感染只是继发的。在大量病例中，最初的生理病理机制是炎症，这可能是由于机械性原因，如胆囊虹吸梗阻以及自主神经控制下的血管运动现象。其组织学病变和病程与临床医学中观察到的相似。这项实验研究的意义在于将急性胆囊炎的病理学与胰腺炎、赖利综合征以及格雷瓜尔和库韦拉尔的内脏中风理论进行比较。
