Dor V, Saab M, Coste P, Sabatier M, Montiglio F
Centre Cardio-Thoracique de Monaco (CCM), Monaco.
Jpn J Thorac Cardiovasc Surg. 1998 May;46(5):389-98. doi: 10.1007/BF03217761.
Most cases of left ventricular aneurysms undergo operation through resection of the exteriorized dyskinetic area with longitudinal suturing of the opening and this technique has been considered by cardiologists (Froehlich et al) to bring no improvement to the morphology and performance of the left ventricle. Some technical modifications have been adopted, such as the septal plicature (Cooley) or circular suturing of the opening (Jatene). Since 1984 our team has used an endoventricular patch, sutured over the contractile area and excluding the akinetic non-resectable scars, bringing a significant and calculable improvement to the left ventricular function. This technique of left ventricular reconstruction (LVR), called endoventricular circular patch plasty (EVCPP) has been already used on more than 750 patients (May 97). Clinical and echographic data for each case are completed by right catheterisation with measurement of the cardiac output, pulmonary arterial pressures (PAP) and programmed ventricular stimulation (PVS), in order to detect eventual ventricular tachycardia (IVT). During left heart catheterisation, the morphology of the left ventricle (LV) is studied on right and left anterior oblique incidences and the LV ejection fraction (EF) is checked globally (GEF) and especially in its contractile portion (CEF). After surgery, a hemodynamic study associated with a PVS, is carried out during the first post-operative month, and again after one year. Results were clinically satisfactory in more than 90% of cases (8.9% of NYHA III-IV), and in more than 90% of cases with ventricular arrhythmia with the hemodynamic persistent EF at one year, superior to the pre-operative CEF. Thus we have to propose the following indications: Elective: This ventricular reconstruction can be recommended for ventricular aneurysms or akinesias with angina, arrhythmias or attacks of cardiac insufficiency, when GEF > 30% and CEF > 40%. The operative mortality rate varies from 1,5 to 3%, which is better than allowing natural evolution. Mandatory: In emergency, when safe immediate circulatory assistance or a cardiac transplant is unavailable, LVR can give hope for survival to more than 80% of patients, whereas natural evolution is without hope. Finally the operative indication is uncertain in two contrasting circumstances: In asymptomatic patients when hemodynamic and angiographic examinations after myocardial infarction show left ventricular dyskinesia. If GEF is below 40% and CEF below 50%, it seems wise to propose LVR in order to prevent unfavourable evolution. In end-stage ischemic cardiomyopathies, if the EF is below 20%, CEF is below 30%, cardiac output is below 1.5 l, and the mean pulmonary pressure is above 25, then a cardiac transplant should be considered. EVCPP with septal exclusion is a safe technique and easily reproduced when associated with coronary revascularization as far as practicable, then EVCPP improves the ventricular function. When associated with sub-total endocardectomy, then EVCPP allows excellent control of VA.
大多数左心室室壁瘤病例通过切除体外运动障碍区域并纵向缝合开口来进行手术,心脏病专家(弗勒利希等人)认为这种技术不会改善左心室的形态和功能。已经采用了一些技术改进措施,如间隔折叠术(库利)或开口的环形缝合(雅泰内)。自1984年以来,我们团队使用了心室内补片,缝合在收缩区域上方,排除无运动能力的不可切除瘢痕,这给左心室功能带来了显著且可计算的改善。这种左心室重建(LVR)技术,称为心室内环形补片成形术(EVCPP),已经应用于750多名患者(1997年5月)。每个病例的临床和超声心动图数据通过右心导管检查来完善,测量心输出量、肺动脉压(PAP)和程控心室刺激(PVS),以检测是否存在室性心动过速(IVT)。在左心导管检查期间,在右前斜位和左前斜位观察左心室(LV)的形态,并整体检查左心室射血分数(EF)(GEF),特别是在其收缩部分(CEF)。手术后,在术后第一个月以及一年后进行与PVS相关的血流动力学研究。超过90%的病例临床结果令人满意(纽约心脏协会III - IV级的占8.9%),超过90%伴有室性心律失常的病例在一年时血流动力学持续EF优于术前CEF。因此我们提出以下适应证:择期:当GEF>30%且CEF>40%时,对于伴有心绞痛、心律失常或心功能不全发作的室壁瘤或运动不能,这种心室重建可被推荐。手术死亡率在1.5%至3%之间,这比任其自然发展要好。强制:在紧急情况下,当无法获得安全的即时循环辅助或心脏移植时,LVR可为超过80%的患者带来生存希望,而任其自然发展则毫无希望。最后,在两种相反的情况下手术适应证不确定:在无症状患者中,心肌梗死后血流动力学和血管造影检查显示左心室运动障碍。如果GEF低于40%且CEF低于50%,为防止不利的病情发展,建议进行LVR似乎是明智的。在终末期缺血性心肌病中,如果EF低于20%,CEF低于30%,心输出量低于1.5升,且平均肺动脉压高于25,则应考虑心脏移植。带间隔排除的EVCPP是一种安全的技术,在可行的情况下与冠状动脉血运重建联合应用时易于重复操作,EVCPP可改善心室功能。当与心内膜次全切除术联合应用时,EVCPP可很好地控制室性心律失常。