Sugimoto T, Minowa T, Uchino H, Shimanuki T, Nakamura C
Department of Surgery, Yamagata Prefectural Nihonkai Hospital, Japan.
Jpn J Thorac Cardiovasc Surg. 1998 May;46(5):482-5. doi: 10.1007/BF03217776.
We report a successful treatment of massive bleeding due to spontaneous splenic rupture after mitral valve replacement. A 61-year-old man was admitted to our hospital for intermittent high fever. An echocardiogram demonstrated a large vegetation on the posterior cusp of the mitral valve and mitral regurgitation of moderate degree. Staphylococcus epidermidis was cultured from his arterial blood. He underwent a mitral valve replacement after 3 weeks of antimicrobiological therapy with penicillin G crystalline and minocycline hydrochloeide. The patient fell into hemorrhagic shock on postoperative day 11 after complaining dull pain on his left upper abdomen for 3 days. A computed tomography demonstrated a splenic rupture and massive hematoma in the retroperitoneum. A splenic arterial embolization was done before splenectomy. The blood and clot of 2800 g were sucked from peritoneal and retroperitoneal cavities. There were no mycotic aneurysms nor abscess but the torn capsule on the swelled and partially necrotic spleen. The patient discharged uneventfully on postoperative day 43. Infective endocarditis frequently causes splenic infarction but rarely splenic rupture. Anticoagulation therapy after mitral valve replacement might have emphasized the bleeding in the patient.
我们报告了一例二尖瓣置换术后因自发性脾破裂导致大量出血的成功治疗病例。一名61岁男性因间歇性高热入住我院。超声心动图显示二尖瓣后叶有一大赘生物及中度二尖瓣反流。从其动脉血中培养出表皮葡萄球菌。在接受青霉素G结晶和盐酸米诺环素3周抗菌治疗后,他接受了二尖瓣置换术。术后第11天,患者在左上腹隐痛3天后陷入失血性休克。计算机断层扫描显示脾破裂及腹膜后大量血肿。在脾切除术前进行了脾动脉栓塞。从腹腔和腹膜后腔吸出2800克血液和血凝块。未见真菌性动脉瘤及脓肿,但肿大且部分坏死的脾脏有包膜撕裂。患者术后第43天顺利出院。感染性心内膜炎常导致脾梗死,但很少引起脾破裂。二尖瓣置换术后的抗凝治疗可能加重了该患者的出血。