Chabrerie A, Ozlen F, Nakajima S, Leventon M E, Atsumi H, Grimson E, Keeve E, Helmers S, Riviello J, Holmes G, Duffy F, Jolesz F, Kikinis R, Black P M
Surgical Planning Laboratory, Department of Radiology, Brigham and Women's Hospital, Boston, Mass 02115, USA.
Pediatr Neurosurg. 1997 Dec;27(6):304-10. doi: 10.1159/000121275.
We have used MRI-based three-dimensional (3D) reconstruction and a real-time, frameless, stereotactic navigation device to facilitate the removal of seizure foci in children suffering from intractable epilepsy. Using this system, the location of subdural grid and strip electrodes is recorded on the 3D model to facilitate focus localization and resection. Ten operations were performed, including 2 girls and 8 boys ranging in age from 3 to 17, during which 3D reconstruction and surgical instrument tracking navigation was used. In all the cases, the patients tolerated the procedure well and showed no postoperative neurological deficits. We believe this to be a valuable tool for a complete and safe resection of seizure foci, thereby reducing the incidence of postoperative neurological deficits and significantly improving the overall quality of life of the patients.
我们使用基于磁共振成像（MRI）的三维（3D）重建技术和实时、无框架立体定向导航设备，以协助切除患有顽固性癫痫的儿童的癫痫病灶。使用该系统，将硬膜下网格电极和条状电极的位置记录在3D模型上，以利于病灶定位和切除。共进行了10例手术，其中包括2名女孩和8名男孩，年龄在3至17岁之间，术中使用了3D重建和手术器械跟踪导航技术。在所有病例中，患者对手术耐受良好，术后未出现神经功能缺损。我们认为这是一种用于完整、安全切除癫痫病灶的有价值工具，从而降低术后神经功能缺损的发生率，并显著提高患者的整体生活质量。
