激素对大鼠条件性味觉厌恶消退率性别差异的影响。

Hormonal influences on sexual dimorphism in rate of extinction of a conditioned taste aversion in rats.

作者信息

Chambers K C

出版信息

J Comp Physiol Psychol. 1976 Sep;90(9):851-6. doi: 10.1037/h0077270.

Abstract

The hormonal influences on the slow extinction rate of a conditioned taste aversion shown by male rats and the fast extinction rate shown by female rats were investigated. When males were castrated, they extinguished as quickly as females. When castrated males were given testosterone propionate replacement, they had a slow extinction rate. Castration had no effect on the extinction rate of females. But when testosterone propionate was administered to castrated or intact females, they had a slow, malelike extinction rate. Thus, sexual dimorphism in the extinction rate of a conditioned taste aversion seems to be due to the activational effects of testosterone.

摘要

研究了激素对雄性大鼠表现出的条件性味觉厌恶消退缓慢率和雌性大鼠表现出的快速消退率的影响。当雄性大鼠被阉割后，它们的消退速度与雌性大鼠一样快。当给阉割后的雄性大鼠注射丙酸睾酮进行替代时，它们的消退速度较慢。阉割对雌性大鼠的消退速度没有影响。但是，当给阉割或未阉割的雌性大鼠注射丙酸睾酮时，它们的消退速度较慢，类似于雄性大鼠。因此，条件性味觉厌恶消退率的性别二态性似乎是由于睾酮的激活作用。