Amaral C F, Campolina D, Dias M B, Bueno C M, Rezende N A
Departamento de Clinica Médica, Faculdade de Medicina da Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil.
Toxicon. 1998 May;36(5):805-8. doi: 10.1016/s0041-0101(97)00132-3.
Clinical and laboratory data from patients who applied a tourniquet (tourniquet group, n = 45) and who did not apply it (non-tourniquet group, n = 52) after being bitten by Crotalus durissus were compared. The patients were treated with 100-200 ml of Crotalus durissus antivenom. The gender, age, time elapsed between bite and hospital admission, dose of antivenom and the frequency of local paresthesia, myalgia and palpebral ptosis did not differ between the two groups. Plasma creatine kinase enzyme activity and partial thromboplastin time, plasma whole venom and crotoxin concentrations and the frequency of acute renal and respiratory failure and number of deaths also did not differ between both groups. Data from this study show the ineffectiveness of tourniquet applied by patients in the fields to reduce the severity of Crotalus durissus envenoming.
比较了被杜氏响尾蛇咬伤后使用止血带的患者(止血带组,n = 45)和未使用止血带的患者(非止血带组,n = 52)的临床和实验室数据。患者接受了100 - 200毫升杜氏响尾蛇抗蛇毒血清治疗。两组在性别、年龄、咬伤至入院的时间、抗蛇毒血清剂量以及局部感觉异常、肌痛和眼睑下垂的发生率方面没有差异。两组的血浆肌酸激酶酶活性和部分凝血活酶时间、血浆全毒液和响尾蛇毒素浓度以及急性肾衰和呼吸衰竭的发生率及死亡人数也没有差异。本研究数据表明,现场患者使用止血带对于减轻杜氏响尾蛇咬伤的严重程度无效。