Hughes A D
Clinical Pharmacology, National Heart and Lung Institute, Imperial College of Science, Technology & Medicine, London, UK.
J Hum Hypertens. 1998 May;12(5):275-81. doi: 10.1038/sj.jhh.1000635.
Angiotensin is an important regulator of blood pressure and exerts both pressor actions and influences growth in the cardiovascular system via the AT1 receptor. This review describes a number of signalling mechanisms involved in vasoconstriction and growth in response to AT1 receptor activation in vascular smooth muscle.
血管紧张素是血压的重要调节因子,通过AT1受体发挥升压作用并影响心血管系统的生长。本综述描述了血管平滑肌中响应AT1受体激活而参与血管收缩和生长的多种信号传导机制。