Oturai A B, Jensen K, Eriksen J, Madsen F F
H:S Bispebjerg Hospital, Multidisciplinaert Smertecenter og neurologisk afdeling.
Ugeskr Laeger. 1998 Jun 22;160(26):3909-12.
The objective was to assess the present condition of patients previously treated with neurosurgical procedures for trigeminal neuralgia (TN). Between 1976 and 1991, 383 patients were treated for TN at the Department of Neurosurgery, Hvidovre Hospital. The latest surgical intervention performed was radiofrequency coagulation (64%), neurectomy (18%), alcohol block (16%), trigeminal tractotomy (1%), and microvascular decompression (1%). Questionnaires were sent to 316 patients treated neurosurgically for trigeminal neuralgia during the 16 year period. After radiofrequency coagulation, neurectomy and alcohol block, 83, 51 and 42% respectively experienced a pain free postoperative period. At present 49, 17 and 18% were without pain and 33, 21 and 36% had less pain compared with the preoperative state. Sequelae were described in 65, 57 and 49% of the patients. The four most common sequelae were hypaesthesia, paraesthesia, eye complaints, and dysaesthesia. If relevant pharmacotherapy has been tried without benefit, radiofrequency coagulation may still be considered as a treatment of trigeminal neuralgia.
目的是评估先前接受过三叉神经痛(TN)神经外科手术治疗的患者的现状。1976年至1991年间,Hvidovre医院神经外科有383例患者接受了TN治疗。最近进行的手术干预包括射频凝固(64%)、神经切除术(18%)、酒精阻滞(16%)、三叉神经束切断术(1%)和微血管减压术(1%)。向在这16年期间接受过TN神经外科治疗的316例患者发送了问卷。射频凝固、神经切除术和酒精阻滞后,分别有83%、51%和42%的患者术后经历了无痛期。目前,与术前状态相比,分别有49%、17%和18%的患者无痛,33%、21%和36%的患者疼痛减轻。分别有65%、57%和49%的患者描述了后遗症。四种最常见的后遗症是感觉减退、感觉异常、眼部不适和感觉障碍。如果尝试了相关药物治疗但无益处,射频凝固仍可被视为三叉神经痛的一种治疗方法。