Murai T, Inui H, Miyahara H, Matsunaga T, Takano H
Department of Otorhinolaryngology, Nara Medical University, Kashihara City, Japan.
Acta Otolaryngol Suppl. 1998;533:30-5. doi: 10.1080/00016489850183719.
We investigated the hemodynamics of the vertebrobasilar system (VBS) using a simulation model tube made of silicone which had different diameters between the bilateral vertebral artery (VA) ducts (stenotic and normal VA ducts). Using the ultrasonic Doppler method. the laterality index (L.I.) of the flow velocity in the VA duct was 32.88%. The flow volume of the anterior inferior cerebellar artery duct and the posterior inferior cerebellar artery duct also had significant laterality. By investigating the effects of the rotatory pulse rate and fluid viscosity, a maximal decrease to below 40-50% of the flow volume of the branches, and to below 71.93% in the mean flow velocity of the basilar artery (BA) duct (BA duct) were observed. and the maximum L.I. increased to 43.15%. When the unilateral stenotic VA duct was occluded by clamping (clamping occlusion), the flow volume profiles of the branches were the same as without clamping occlusion. The L.I. showed no significant changes and the maximal decrease in the mean flow velocity of the BA duct was 68.61%. Using the laser Doppler method, the flow velocity distribution of the BA duct was shifted towards the side of the stenotic VA duct. These results suggest that the rheological dynamics in the main vessels can certainly reflect the posterior circulatory dynamics, and that modulating factors also aggravate the hemodynamics of the VBS with this disorder.
我们使用由硅胶制成的模拟模型管研究了椎基底动脉系统（VBS）的血流动力学，该模型管的双侧椎动脉（VA）导管（狭窄和正常VA导管）之间具有不同直径。采用超声多普勒法，VA导管内血流速度的侧别指数（L.I.）为32.88%。小脑前下动脉导管和小脑后下动脉导管的血流量也有明显的侧别差异。通过研究旋转脉搏率和流体粘度的影响，观察到分支血流量最大下降至低于40 - 50%，基底动脉（BA）导管平均血流速度最大下降至低于71.93%，最大L.I.增加至43.15%。当通过夹闭（夹闭闭塞）使单侧狭窄的VA导管闭塞时，分支的血流量分布与未夹闭闭塞时相同。L.I.无显著变化，BA导管平均血流速度最大下降为68.61%。使用激光多普勒法，BA导管的血流速度分布向狭窄VA导管一侧偏移。这些结果表明，主要血管中的流变动力学肯定能反映后循环动力学，并且调节因素也会加重这种疾病状态下VBS的血流动力学。
