一般应激转录因子σB和芽孢形成转录因子σH各自有助于枯草芽孢杆菌在极端生长条件下的存活。
General stress transcription factor sigmaB and sporulation transcription factor sigmaH each contribute to survival of Bacillus subtilis under extreme growth conditions.
作者信息
Gaidenko T A, Price C W
机构信息
Department of Food Science and Technology, University of California, Davis, California 95616, USA.
出版信息
J Bacteriol. 1998 Jul;180(14):3730-3. doi: 10.1128/JB.180.14.3730-3733.1998.
Abstract
The general stress response of the bacterium Bacillus subtilis is controlled by the sigmaB transcription factor. Here we show that loss of sigmaB reduces stationary-phase viability 10-fold in either alkaline or acidic media and reduces cell yield in media containing ethanol. We further show that loss of the developmental transcription factor sigmaH also has a marked effect on stationary-phase viability under these conditions and that this effect is independent from the simple loss of sporulation ability.
摘要
枯草芽孢杆菌的一般应激反应由σB转录因子控制。在此我们表明，在碱性或酸性培养基中，σB缺失会使稳定期存活率降低10倍，并且在含有乙醇的培养基中会降低细胞产量。我们进一步表明，发育转录因子σH的缺失在这些条件下对稳定期存活率也有显著影响，并且这种影响与孢子形成能力的简单丧失无关。
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