Miyazaki S
Second Department of Medicine, Kurume University School of Medicine, Japan.
Kurume Med J. 1998;45(1):95-103. doi: 10.2739/kurumemedj.45.95.
We evaluated the diagnostic efficacy of high-frequency (20 MHz) ultrasound probe (HFUP) for the staging of invasive depth of colorectal tumors. The subjects were 27 patients with colorectal tumorous lesions who were treated by endoscopic or surgical operation (11 patients with lesions remaining in the mucosa, 13 patients with submucosal cancer, and 3 patients with cancer invading the muscularis propria or deeper layers). Considering the previous reports that endoscopic mucosal resection (EMR) is indicated in cases of tumors remaining in the mucosa or cancer slightly invading the submucosal layer, we divided the submucosal layer vertically into three equal areas (most superficial, middle and deepest areas which were referred to as sm1, sm2 and sm3, respectively). The depth of tumor invasion in histological specimens was compared to the depth of tumor invasion as assessed preoperatively using the HFUP. The HFUP-based diagnosis was identical to the histological diagnosis in 86.4% of all cases, when the depth of tumor invasion was rated on a three-point scale: (i) m-sm1, (ii) sm2-sm3 or (iii) mp or deeper. These results indicate that the HFUP is very useful in selecting a therapeutic method for colorectal tumors.
我们评估了高频（20兆赫）超声探头（HFUP）对结直肠肿瘤浸润深度分期的诊断效能。研究对象为27例接受内镜或手术治疗的结直肠肿瘤性病变患者（11例病变局限于黏膜层，13例为黏膜下癌，3例癌浸润至固有肌层或更深层）。鉴于既往报道提示，对于局限于黏膜层或轻度浸润黏膜下层的肿瘤患者可行内镜黏膜切除术（EMR），我们将黏膜下层垂直划分为三个相等区域（最表层、中间层和最深层区域，分别称为sm1、sm2和sm3）。将组织学标本中的肿瘤浸润深度与术前使用HFUP评估的肿瘤浸润深度进行比较。当肿瘤浸润深度按三分制评分时：（i）m-sm1，（ii）sm2-sm3，或（iii）mp或更深，基于HFUP的诊断在所有病例中有86.4%与组织学诊断一致。这些结果表明，HFUP在选择结直肠肿瘤的治疗方法方面非常有用。
