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变性静脉同种异体移植物作为民用血管损伤的动脉替代物:30个月的经验。

Denatured venous homograft as an arterial substitute in civilian vascular injuries. Thirty months' experience.

作者信息

La Barbera G, Pumilia G, La Marca G, Martino A

机构信息

Department of Vascular Surgery, Civic Hospital Benfratelli of Palermo, Italy.

出版信息

Eur J Vasc Endovasc Surg. 1998 Jun;15(6):467-71. doi: 10.1016/s1078-5884(98)80104-4.

Abstract

OBJECTIVES

Autologous saphenous vein (ASV) for arterial reconstruction, in vascular limb injuries is the graft material of choice. Denatured saphenous vein homograft (DSVH), thanks to its characteristics of readily available autologous biological prosthesis, has been proposed as alternative. We report our prospective experience with DSVH employed for arterial reconstruction in civilian limb vascular injuries.

MATERIALS

From January 1994 to June 1996, DSVH was implanted in 16 male patients (pts.) treated for arterial civilian injuries of eight upper limbs and eight lower limbs.

METHODS

In 14 cases it was performed as an interposition graft and in two cases a bypass. We performed a 30-month follow-up and a 20-month mean follow-up.

RESULTS

Four patients had graft thrombosis at the first postoperative week and were submitted to the replacement of the graft with reappearance of distal arterial pulse; one of them had graft failure at the fifth postoperative week and because the necrosis due to extensive soft tissue damage, he was submitted to limb amputation. After 30-months' follow-up we obtained 75% primary patency rate and 93% secondary patency rate.

CONCLUSIONS

In the absence of suitable ASV, DSVH appears to be an interesting alternative for arterial repair in limbs in civilian vascular injuries.

摘要

目的

在肢体血管损伤中,自体大隐静脉(ASV)是动脉重建的首选移植材料。变性大隐静脉同种异体移植物(DSVH)因其具有易于获取的自体生物假体特性,已被提议作为替代材料。我们报告了我们使用DSVH进行 civilian 肢体血管损伤动脉重建的前瞻性经验。

材料

1994年1月至1996年6月,DSVH被植入16例男性患者体内,这些患者因上肢和下肢的 civilian 动脉损伤接受治疗。

方法

14例采用间置移植,2例采用旁路移植。我们进行了30个月的随访,平均随访20个月。

结果

4例患者在术后第一周出现移植血管血栓形成,并接受了移植血管置换,远端动脉搏动恢复;其中1例在术后第五周出现移植血管失败,由于广泛软组织损伤导致坏死,接受了截肢手术。经过30个月的随访,我们获得了75%的一期通畅率和93%的二期通畅率。

结论

在没有合适的ASV的情况下,DSVH似乎是 civilian 血管损伤肢体动脉修复的一种有趣替代方案。

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