Megrelishvili R I, Glezer G A, Ryff I M, Cherpachenko N M, Sharov V G
Kardiologiia. 1976 Feb;16(2):137-40.
Under significant physical exercises the myocardium of rats displays distinct enzymopathy, increased permeability of the cell membranes with a considerable dispersion of plasma proteins and damage to the ultrastructures of the myocytes. The employment of pyridoxilate reduces the severity of the damaging reaction, and to some extent normalizes the structure of the cellular and sub-cellular elements of the myocardium. This indicates to the prospects of using the regulators of cellular respiration under total and tissue hypoxia.
在剧烈体育锻炼下，大鼠的心肌表现出明显的酶病，细胞膜通透性增加，血浆蛋白有相当大的分散，并且心肌细胞超微结构受损。使用吡哆醛酸盐可降低损伤反应的严重程度，并在一定程度上使心肌细胞和亚细胞成分的结构正常化。这表明在全身和组织缺氧情况下使用细胞呼吸调节剂具有前景。
