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A型肉毒杆菌毒素,用于治疗与颅周肌肉紧张相关的难治性头痛的辅助疗法。

Botulinum toxin A, adjunctive therapy for refractory headaches associated with pericranial muscle tension.

作者信息

Wheeler A H

机构信息

Charlotte Spine Center, NC 28207, USA.

出版信息

Headache. 1998 Jun;38(6):468-71. doi: 10.1046/j.1526-4610.1998.3806468.x.

DOI:10.1046/j.1526-4610.1998.3806468.x
PMID:9664753
Abstract

Pericranial muscle tension may contribute to the development of facial discomfort, chronic daily headache, and migraine-type headache. Elimination of pericranial muscle tension may reduce associated myalgia and counteract influences that can trigger secondary headaches which fall within the migraine continuum. Four patients with chronic, predominantly tension-type headaches and associated pericranial muscle tension failed prolonged conventional treatment and, therefore, symptomatic areas were treated with botulinum toxin A. This alleviated myalgia and reduced the severity and frequency of migraine-type headaches with a concomitant reduction in subsequent medical and physical therapy interventions. Judicious use of botulinum toxin A into defined areas of pericranial muscle tension may be useful for reducing primary myalgia and secondary headache.

摘要

颅周肌肉紧张可能导致面部不适、慢性每日头痛和偏头痛样头痛的发生。消除颅周肌肉紧张可能减轻相关的肌痛,并抵消可能引发偏头痛连续体范围内继发性头痛的影响。4例患有慢性、主要为紧张型头痛及相关颅周肌肉紧张的患者,长期常规治疗无效,因此,对有症状的部位注射A型肉毒毒素进行治疗。这减轻了肌痛,降低了偏头痛样头痛的严重程度和发作频率,同时减少了后续的药物和物理治疗干预。在颅周肌肉紧张的特定区域明智地使用A型肉毒毒素,可能有助于减轻原发性肌痛和继发性头痛。

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Botulinum toxin A, adjunctive therapy for refractory headaches associated with pericranial muscle tension.A型肉毒杆菌毒素,用于治疗与颅周肌肉紧张相关的难治性头痛的辅助疗法。
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