Böke W, Thiel H J, Winter R
Klin Monbl Augenheilkd. 1976 Apr;168(4):483-92.
The corneal pathology in rheumatoid arthritis and Sjögren's syndrome is described with emphasis on rheumatic keratomalacia. This particular disorder whether affecting the central and paracentral or the peripheral parts of the cornea is characterized by thinning of the corneal stroma, loss of epithelium, ulceration and eventually by corneal perforation. 7 cases are reported. Reduced tear production and simultaneous corticosteroid treatment seem to be the essential pathogenetic factors of this corneal disease. Therapeutic consequences and differential diagnosis are discussed.
描述了类风湿性关节炎和干燥综合征的角膜病理学,重点是风湿性角膜软化症。这种特殊病症,无论影响角膜中央和旁中央部分还是周边部分,其特征均为角膜基质变薄、上皮脱落、溃疡,最终导致角膜穿孔。报告了7例病例。泪液分泌减少和同时进行的皮质类固醇治疗似乎是这种角膜疾病的主要致病因素。讨论了治疗结果和鉴别诊断。