Lázaro-Carrasco M T, Ussetti Gil P, Ferreiro M J, Carreño M C, Pablo Gafa A, García López F, Varela A, Estada Girauta J A
Servicio de Neumología, Clínica Puerta de Hierro, Madrid.
Arch Bronconeumol. 1998 Jun;34(6):285-8. doi: 10.1016/s0300-2896(15)30414-2.
The objective of this study was to analyze patient survival after lung transplants performed at the Puerta de Hierro clinic in Madrid (Spain) between 1991 and 1996. Survival probability was 65% after one year and 50% after three years. We found no significant differences in survival related to sex or type of transplant. Early survival tended to be higher for the last two years analyzed (71%) than for the first two (55%) (p < 0.00001). The rate was 100% for patients with cystic fibrosis and 0% for pulmonary hypertension and lymphangiomyomatosis. Short- and medium-term lung function results were good in surviving patients who did not develop obliterating bronchiolitis. We conclude that actuarial survival after lung transplant in our program is comparable to that reported in the literature. There are no significant differences related to sex, type of transplant or period. Survival varies greatly, however, depending on disease.
本研究的目的是分析1991年至1996年在西班牙马德里希耶罗港诊所进行肺移植后的患者生存率。一年后的生存概率为65%,三年后的生存概率为50%。我们发现生存率在性别或移植类型方面没有显著差异。分析的最后两年的早期生存率(71%)往往高于前两年(55%)(p<0.00001)。囊性纤维化患者的生存率为100%,肺动脉高压和淋巴管肌瘤病患者的生存率为0%。未发生闭塞性细支气管炎的存活患者的短期和中期肺功能结果良好。我们得出结论,我们项目中肺移植后的精算生存率与文献报道的相当。在性别、移植类型或时期方面没有显著差异。然而,生存率因疾病而异。