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[长时间暴露于高压环境(N2 - 02,5个大气压)下的人体肾上腺功能]

[Human adrenal function during prolonged exposure to hyperbaric conditions (N2-02, 5 atm)].

作者信息

Turubiner N M

出版信息

Kosm Biol Aviakosm Med. 1976 May-Jun;10(3):32-7.

PMID:966675
Abstract

Test subjects were exposed to a nitrogen-oxygen atmosphere at 5 ata, performing various activities. The adrenal function of the subjects was examined with respect to the catecholamine and corticosteroids excretion in the urine. During adaptation to the environment the excretion of catecholamines and corticosteroids varied phasically. After 3 days of the 7-day exposure to the hyperbaric atmosphere and during decompression the excretion of norepinephrine increased and that of corticosteroids, particularly 17-corticosteroids, decreased. The diurnal rhythm of the excretion changed though the life regimen of the test subjects remained unaltered. These variations can be considered as adaptive-protective responses of the human body.

摘要

实验对象在5个绝对大气压的氮氧环境中进行各种活动。通过检测尿中儿茶酚胺和皮质类固醇的排泄情况来检查实验对象的肾上腺功能。在适应环境的过程中,儿茶酚胺和皮质类固醇的排泄呈阶段性变化。在7天高压环境暴露的第3天后以及减压过程中,去甲肾上腺素的排泄增加,而皮质类固醇,尤其是17-皮质类固醇的排泄减少。尽管实验对象的生活作息保持不变,但排泄的昼夜节律发生了变化。这些变化可被视为人体的适应性保护反应。

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