Bada H S, Bauer C R, Shankaran S, Lester B, Wright L L, Verter J, Smeriglio V L, Finnegan L P, Maza P L
University of Tennessee, Memphis 38163, USA.
Ann N Y Acad Sci. 1998 Jun 21;846:431-4.
In summary, we found that the prevalence of CNS/ANS signs was significantly higher in the infants exposed to cocaine and/or opiates than in nonexposed infants. However, the prevalence of a large number of these signs was less than 5%. The prevalence rates of these signs are lower when exposure involved cocaine only; thus, their assessment has limited clinical utility.
总之,我们发现暴露于可卡因和/或阿片类药物的婴儿中,中枢神经系统/自主神经系统体征的患病率显著高于未暴露的婴儿。然而,这些体征中大量体征的患病率低于5%。仅暴露于可卡因时这些体征的患病率较低;因此,对它们的评估临床效用有限。