Borysov V A, Cheusova Z V, Molozhava O S
Taras Shevchenko University, Kiev.
Fiziol Zh (1994). 1998;44(4):3-9.
Activity of transfer-factor (TF) delayed type hypersensitivity in allogenic and xenogeneic have studied. Guinea pigs was been sensibilized Soluble antigens and whole cells Candida albicans for production TF. Both TF expressed non specific and specific activity in the guinea pig and mouse leucocytes inhibition migration in vitro and delayed type hypersensitivity in mica. Activity of TF to cellular antigen was lower then TF to soluble antigen in xenogeneic systems. However TF activity was some low for whole cells in xenogeneic systems.
已经研究了转移因子(TF)在同种异体和异种延迟型超敏反应中的活性。用可溶性抗原和白色念珠菌全细胞使豚鼠致敏以产生TF。两种TF在豚鼠和小鼠白细胞体外抑制迁移以及在云母中的延迟型超敏反应中均表现出非特异性和特异性活性。在异种系统中,TF对细胞抗原的活性低于对可溶性抗原的活性。然而,在异种系统中,TF对全细胞的活性有些低。